The Gαi protein subclass selectivity to the dopamine D(2) receptor is also decided by their location at the cell membrane

BACKGROUND: G protein-coupled receptor (GPCR) signaling via heterotrimeric G proteins plays an important role in the cellular regulation of responses to external stimuli. Despite intensive structural research, the mechanism underlying the receptor–G protein coupling of closely related subtypes of Gα...

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Detalles Bibliográficos
Autores principales: Polit, Agnieszka, Rysiewicz, Beata, Mystek, Paweł, Błasiak, Ewa, Dziedzicka-Wasylewska, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731117/
https://www.ncbi.nlm.nih.gov/pubmed/33308256
http://dx.doi.org/10.1186/s12964-020-00685-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731117/
https://www.ncbi.nlm.nih.gov/pubmed/33308256
http://dx.doi.org/10.1186/s12964-020-00685-9

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