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Compact Bidirectional Promoters for Dual-Gene Expression in a Sleeping Beauty Transposon

Promoter choice is an essential consideration for transgene expression in gene therapy. The expression of multiple genes requires ribosomal entry or skip sites, or the use of multiple promoters. Promoter systems comprised of two separate, divergent promoters may significantly increase the size of ge...

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Detalles Bibliográficos
Autores principales: He, Kevin, Rad, S. M. Ali Hosseini, Poudel, Aarati, McLellan, Alexander Donald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731152/
https://www.ncbi.nlm.nih.gov/pubmed/33291599
http://dx.doi.org/10.3390/ijms21239256