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The Palladium(II) Complex of Aβ(4−16) as Suitable Model for Structural Studies of Biorelevant Copper(II) Complexes of N-Truncated Beta-Amyloids

The A [Formula: see text] peptide is a major beta-amyloid species in the human brain, forming toxic aggregates related to Alzheimer’s Disease. It also strongly chelates Cu(II) at the N-terminal Phe-Arg-His ATCUN motif, as demonstrated in A [Formula: see text] and A [Formula: see text] model peptides...

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Detalles Bibliográficos
Autores principales: Mital, Mariusz, Szutkowski, Kosma, Bossak-Ahmad, Karolina, Skrobecki, Piotr, Drew, Simon C., Poznański, Jarosław, Zhukov, Igor, Frączyk, Tomasz, Bal, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731285/
https://www.ncbi.nlm.nih.gov/pubmed/33276669
http://dx.doi.org/10.3390/ijms21239200