Autosomal dominant polycystic kidney disease and pioglitazone for its therapy: a comprehensive review with an emphasis on the molecular pathogenesis and pharmacological aspects

Autosomal dominant polycystic kidney disease (ADPKD) is an inherited chronic kidney disorder (CKD) that is characterized by the development of numerous fluid-filled cysts in kidneys. It is caused either due to the mutations in the PKD1 or PKD2 gene that encodes polycystin-1 and polycystin-2, respect...

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Detalles Bibliográficos
Autores principales: Saini, Aryendu Kumar, Saini, Rakesh, Singh, Shubham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731470/
https://www.ncbi.nlm.nih.gov/pubmed/33308138
http://dx.doi.org/10.1186/s10020-020-00246-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731470/
https://www.ncbi.nlm.nih.gov/pubmed/33308138
http://dx.doi.org/10.1186/s10020-020-00246-3

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