ALKBH2 inhibition alleviates malignancy in colorectal cancer by regulating BMI1-mediated activation of NF-κB pathway

BACKGROUND: The alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase (ALKBH2) gene is involved in DNA repair and is expressed in different types of malignancies. However, the role of ALKBH2 in colorectal carcinoma (CRC) remains unclear. This study aimed to explore the potential mechanism of ALK...

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Detalles Bibliográficos
Autores principales: Ke, Bingxin, Ye, Kejun, Cheng, Shaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731553/
https://www.ncbi.nlm.nih.gov/pubmed/33302959
http://dx.doi.org/10.1186/s12957-020-02106-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731553/
https://www.ncbi.nlm.nih.gov/pubmed/33302959
http://dx.doi.org/10.1186/s12957-020-02106-0

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