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Antenatal pentoxifylline therapy to prevent endotoxin-induced fetal injury in the preterm goat model

OBJECTIVE: Pentoxifylline (PTX) has immunomodulatory properties and is known to reduce sepsis-associated infant mortality. We aimed to evaluate maternal oral and intra-amniotic administration of PTX for the prevention of fetal inflammation and injury in a caprine model. MATERIALS AND METHODS: Inflam...

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Detalles Bibliográficos
Autores principales: Sezik, Mekin, Köker, Afşin, Özmen, Özlem, Halıgür, Mehmet, Kaşıkcı, Duygu, Aydoğan, Ahmet, Özatik, Orhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731608/
https://www.ncbi.nlm.nih.gov/pubmed/33343972
http://dx.doi.org/10.4274/tjod.galenos.2020.19794