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Hypoxic exosomes orchestrate tumorigenesis: molecular mechanisms and therapeutic implications

The solid tumor microenvironment possesses a hypoxic condition, which promotes aggressiveness and resistance to therapies. Hypoxic tumor cells undergo broadly metabolic and molecular adaptations and communicate with surrounding cells to provide conditions promising for their homeostasis and metastas...

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Detalles Bibliográficos
Autores principales: Jafari, Reza, Rahbarghazi, Reza, Ahmadi, Mahdi, Hassanpour, Mehdi, Rezaie, Jafar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731629/
https://www.ncbi.nlm.nih.gov/pubmed/33302971
http://dx.doi.org/10.1186/s12967-020-02662-9