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Hypoxic exosomes orchestrate tumorigenesis: molecular mechanisms and therapeutic implications
The solid tumor microenvironment possesses a hypoxic condition, which promotes aggressiveness and resistance to therapies. Hypoxic tumor cells undergo broadly metabolic and molecular adaptations and communicate with surrounding cells to provide conditions promising for their homeostasis and metastas...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731629/ https://www.ncbi.nlm.nih.gov/pubmed/33302971 http://dx.doi.org/10.1186/s12967-020-02662-9 |