Cargando…

Hypoxic exosomes orchestrate tumorigenesis: molecular mechanisms and therapeutic implications

The solid tumor microenvironment possesses a hypoxic condition, which promotes aggressiveness and resistance to therapies. Hypoxic tumor cells undergo broadly metabolic and molecular adaptations and communicate with surrounding cells to provide conditions promising for their homeostasis and metastas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jafari, Reza, Rahbarghazi, Reza, Ahmadi, Mahdi, Hassanpour, Mehdi, Rezaie, Jafar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731629/ https://www.ncbi.nlm.nih.gov/pubmed/33302971 http://dx.doi.org/10.1186/s12967-020-02662-9

Ejemplares similares

Exosomal cargos modulate autophagy in recipient cells via different signaling pathways
por: Hassanpour, Mehdi, et al.
Publicado: (2020)

Evaluation of histopathological changes and exosomal biogenesis in pulmonary tissue of diabetic rats
por: Delkhosh, Aref, et al.
Publicado: (2022)

Type 2 diabetes mellitus induced autophagic response within pulmonary tissue in the rat model
por: Bayazidi, Mohammad Ghader, et al.
Publicado: (2023)

Asthmatic condition induced the activity of exosome secretory pathway in rat pulmonary tissues
por: Almohammai, Asheed, et al.
Publicado: (2021)

Tumor cells derived-exosomes as angiogenenic agents: possible therapeutic implications
por: Ahmadi, Mahdi, et al.
Publicado: (2020)

Effects of crocin on T-bet/GATA-3 ratio, and miR-146a and miR-106a expression levels in lung tissue of ovalbumin-sensitized mice
por: Aslani, Mohammad Reza, et al.
Publicado: (2022)

Systemic administration of c-Kit(+) cells diminished pulmonary and vascular inflammation in rat model of chronic asthma
por: Taghizadeh, Sajjad, et al.
Publicado: (2022)

Autophagy modulation altered differentiation capacity of CD146(+) cells toward endothelial cells, pericytes, and cardiomyocytes
por: Hassanpour, Mehdi, et al.
Publicado: (2020)

The versatile role of exosomes in human retroviral infections: from immunopathogenesis to clinical application
por: Rezaie, Jafar, et al.
Publicado: (2021)

Exosome-orchestrated hypoxic tumor microenvironment
por: Meng, Wanrong, et al.
Publicado: (2019)

Type 2 Diabetes Mellitus Provokes Rat Immune Cells Recruitment into the Pulmonary Niche by Up-regulation of Endothelial Adhesion Molecules
por: Zarafshan, Eghbal, et al.
Publicado: (2022)

Role of autophagy in atherosclerosis: foe or friend?
por: Hassanpour, Mehdi, et al.
Publicado: (2019)

Mesenchymal stem cell derived-exosomes: a modern approach in translational medicine
por: Nikfarjam, Sepideh, et al.
Publicado: (2020)

Comparison the therapeutic effects of bone marrow CD144(+) endothelial cells and CD146(+) mesenchymal stem cells in POF rats
por: Nazdikbin Yamchi, Nahideh, et al.
Publicado: (2023)

Chronic Exposure of Human Endothelial Progenitor Cells to Diabetic Condition Abolished the Regulated Kinetics Activity of Exosomes
por: Hassanpour, Mehdi, et al.
Publicado: (2018)

An Examination of the Putative Role of Melatonin in Exosome Biogenesis
por: Amini, Hassan, et al.
Publicado: (2021)

Engineered Exosomes for Tumor-Targeted Drug Delivery: A Focus on Genetic and Chemical Functionalization
por: Akbari, Ali, et al.
Publicado: (2022)

Exendin-4 as a Versatile Therapeutic Agent for the Amelioration of Diabetic Changes
por: Rajabi, Hadi, et al.
Publicado: (2022)

Harnessing Normal and Engineered Mesenchymal Stem Cells Derived Exosomes for Cancer Therapy: Opportunity and Challenges
por: Ahmadi, Mahdi, et al.
Publicado: (2022)

Autophagy stimulation delayed biological aging and decreased cardiac differentiation in rabbit mesenchymal stem cells
por: Hassanpour, Mehdi, et al.
Publicado: (2021)

Cardiac progenitor cells application in cardiovascular disease
por: Amini, Hassan, et al.
Publicado: (2017)

Unraveling the therapeutic effects of mesenchymal stem cells in asthma
por: Mirershadi, Fatemeh, et al.
Publicado: (2020)

Interplay between exosomes and autophagy machinery in pain management: State of the art
por: Morteza Bagi, Hamidreza, et al.
Publicado: (2022)

Role of hypoxic exosomes and the mechanisms of exosome release in the CNS under hypoxic conditions
por: Yang, Rong, et al.
Publicado: (2023)

A reversal of age-dependent proliferative capacity of endothelial progenitor cells from different species origin in in vitro condition
por: Hassanpour, Mehdi, et al.
Publicado: (2016)

Distinct role of autophagy on angiogenesis: highlights on the effect of autophagy in endothelial lineage and progenitor cells
por: Hassanpour, Mehdi, et al.
Publicado: (2018)

Potential therapeutic application of mesenchymal stem cell-derived exosomes in SARS-CoV-2 pneumonia
por: Akbari, Ali, et al.
Publicado: (2020)

The role of extracellular vesicles in COVID-19 virus infection
por: Hassanpour, Mehdi, et al.
Publicado: (2020)

c-kit+ cells offer hopes in ameliorating asthmatic pathologies via regulation of miRNA-133 and miRNA-126
por: Rahbarghazi, Reza, et al.
Publicado: (2021)

Molecular Signaling in Tumorigenesis of Gastric Cancer
por: Molaei, Fatemeh, et al.
Publicado: (2018)

Hollow Alginate-Poly-L-Lysine-Alginate Microspheres Promoted an Epithelial-Mesenchymal Transition in Human Colon Adenocarcinoma Cells
por: Saberianpour, Shirin, et al.
Publicado: (2020)

Orchestration of H3K27 methylation: mechanisms and therapeutic implication
por: Pan, Mei-Ren, et al.
Publicado: (2017)

Multiple Myeloma Cell-Derived Exosomes: Implications on Tumorigenesis, Diagnosis, Prognosis and Therapeutic Strategies
por: Allegra, Alessandro, et al.
Publicado: (2021)

Protein corona and exosomes: new challenges and prospects
por: Heidarzadeh, Morteza, et al.
Publicado: (2023)

Applications, challenges and prospects of mesenchymal stem cell exosomes in regenerative medicine
por: Rezabakhsh, Aysa, et al.
Publicado: (2021)

Exosomal delivery of therapeutic modulators through the blood–brain barrier; promise and pitfalls
por: Heidarzadeh, Morteza, et al.
Publicado: (2021)

Role of melatonin in the angiogenesis potential; highlights on the cardiovascular disease
por: Rahbarghazi, Afshin, et al.
Publicado: (2021)

Survivin and Tumorigenesis: Molecular Mechanisms and Therapeutic Strategies
por: Chen, Xun, et al.
Publicado: (2016)

Dexosomes as a cell-free vaccine for cancer immunotherapy
por: Nikfarjam, Sepideh, et al.
Publicado: (2020)

Emerging role of exosomes in the pathology of chronic obstructive pulmonary diseases; destructive and therapeutic properties
por: Rajabi, Hadi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ta4kdbr2fhmv2je6mu2p7a2nks