Knockdown of Forkhead box A1 suppresses the tumorigenesis and progression of human colon cancer cells through regulating the phosphatase and tensin homolog/Akt pathway

BACKGROUND: This study aimed to evaluate the role and the underlying mechanisms of Forkhead box A1 (encoded by FOXA1) in colon cancer. METHODS: We analyzed FOXA1 mRNA and protein expression in colon cancer tissues and cell lines. We also silenced FOXA1 expression in HCT116 and SW480 cells to evaluat...

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Detalles Bibliográficos
Autores principales: Pan, Jie, Xu, Zongbin, Xu, Meifang, Lin, Xiaoyan, Lin, Bingqiang, Lin, Mengxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Pre-Clinical Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731712/
https://www.ncbi.nlm.nih.gov/pubmed/33296605
http://dx.doi.org/10.1177/0300060520971453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731712/
https://www.ncbi.nlm.nih.gov/pubmed/33296605
http://dx.doi.org/10.1177/0300060520971453

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