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LncRNA-GAS5 Inhibits Expression of miR 103 and Ameliorates the Articular Cartilage in Adjuvant-Induced Arthritis in Obese Mice

We explored whether long noncoding RNA growth arrest-specific transcript 5 (LncRNA-GAS5) small interfering RNA (siRNA) reduced cartilage destruction in obese mice with adjuvant-induced arthritis. We studied the effects of LncRNA-GAS5 siRNA on the polyarthritis index; hind paw swelling; and the serum...

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Detalles Bibliográficos
Autores principales: Chen, Hongwei, He, Chuan, Liu, Yan, Li, Xiaolin, Zhang, Chaoju, Qin, Qunyan, Pang, Qixiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731719/
https://www.ncbi.nlm.nih.gov/pubmed/33343265
http://dx.doi.org/10.1177/1559325820942718