MCL-1 inhibitors, fast-lane development of a new class of anti-cancer agents

Cell death escape is one of the most prominent features of tumor cells and closely linked to the dysregulation of members of the Bcl-2 family of proteins. Among those, the anti-apoptotic family member myeloid cell leukemia-1 (MCL-1) acts as a master regulator of apoptosis in various human malignanci...

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Detalles Bibliográficos
Autores principales: Bolomsky, Arnold, Vogler, Meike, Köse, Murat Cem, Heckman, Caroline A., Ehx, Grégory, Ludwig, Heinz, Caers, Jo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731749/
https://www.ncbi.nlm.nih.gov/pubmed/33308268
http://dx.doi.org/10.1186/s13045-020-01007-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731749/
https://www.ncbi.nlm.nih.gov/pubmed/33308268
http://dx.doi.org/10.1186/s13045-020-01007-9

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