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The dysregulation of the hypothalamic–pituitary–adrenal axis in diet-induced prediabetic male Sprague Dawley rats

BACKGROUND: Altered function of the hypothalamic–pituitary–adrenal (HPA) axis in type 2 diabetic patients, a condition preceded by pre-diabetes, has been shown to increase the risk of depression as well as cause downstream effects resulting in upregulation of gluconeogenesis and dyslipidemia. In add...

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Detalles Bibliográficos
Autores principales: Mosili, Palesa, Mkhize, Bongeka Cassandra, Ngubane, Phikelelani, Sibiya, Ntethelelo, Khathi, Andile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731754/
https://www.ncbi.nlm.nih.gov/pubmed/33308255
http://dx.doi.org/10.1186/s12986-020-00532-1