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Hypoxia-preconditioned adipose-derived stem cells combined with scaffold promote urethral reconstruction by upregulation of angiogenesis and glycolysis

RATIONALE: Tissue engineering is a promising alternative for urethral reconstruction, and adipose-derived stem cells (ADSCs) are widely used as seeding cells. Hypoxia preconditioning can significantly enhance the therapeutic effects of ADSCs. The low oxygen tension of postoperative wound healing is...

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Detalles Bibliográficos
Autores principales: Wan, Xiang, Xie, Min-kai, Xu, Huan, Wei, Zi-wei, Yao, Hai-jun, Wang, Zhong, Zheng, Da-chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731784/
https://www.ncbi.nlm.nih.gov/pubmed/33308306
http://dx.doi.org/10.1186/s13287-020-02052-4