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RNA Sequencing of Human Peripheral Blood Cells Indicates Upregulation of Immune-Related Genes in Huntington's Disease

Huntington's disease (HD) is an autosomal dominantly inherited neurodegenerative disorder caused by a trinucleotide repeat expansion in the Huntingtin gene. As disease-modifying therapies for HD are being developed, peripheral blood cells may be used to indicate disease progression and to monit...

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Detalles Bibliográficos
Autores principales: Andrade-Navarro, Miguel A., Mühlenberg, Katja, Spruth, Eike J., Mah, Nancy, González-López, Adrián, Andreani, Tommaso, Russ, Jenny, Huska, Matthew R., Muro, Enrique M., Fontaine, Jean-Fred, Amstislavskiy, Vyacheslav, Soldatov, Alexei, Nietfeld, Wilfried, Wanker, Erich E., Priller, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731869/
https://www.ncbi.nlm.nih.gov/pubmed/33329316
http://dx.doi.org/10.3389/fneur.2020.573560