Cargando…
RNA Sequencing of Human Peripheral Blood Cells Indicates Upregulation of Immune-Related Genes in Huntington's Disease
Huntington's disease (HD) is an autosomal dominantly inherited neurodegenerative disorder caused by a trinucleotide repeat expansion in the Huntingtin gene. As disease-modifying therapies for HD are being developed, peripheral blood cells may be used to indicate disease progression and to monit...
Autores principales: | Andrade-Navarro, Miguel A., Mühlenberg, Katja, Spruth, Eike J., Mah, Nancy, González-López, Adrián, Andreani, Tommaso, Russ, Jenny, Huska, Matthew R., Muro, Enrique M., Fontaine, Jean-Fred, Amstislavskiy, Vyacheslav, Soldatov, Alexei, Nietfeld, Wilfried, Wanker, Erich E., Priller, Josef |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731869/ https://www.ncbi.nlm.nih.gov/pubmed/33329316 http://dx.doi.org/10.3389/fneur.2020.573560 |
Ejemplares similares
-
Huntington's disease: from gene to potential therapy
por: Lehrach, Hans, et al.
Publicado: (2001) -
Small, Seeding-Competent Huntingtin Fibrils Are Prominent Aggregate Species in Brains of zQ175 Huntington’s Disease Knock-in Mice
por: Schindler, Franziska, et al.
Publicado: (2021) -
Ku70 Alleviates Neurodegeneration in Drosophila Models of Huntington's Disease
por: Tamura, Takuya, et al.
Publicado: (2011) -
Correction: Ku70 Alleviates Neurodegeneration in Drosophila Models of Huntington's Disease
por: Tamura, Takuya, et al.
Publicado: (2012) -
Assessment of Ethanol-Induced Toxicity on iPSC-Derived Human Neurons Using a Novel High-Throughput Mitochondrial Neuronal Health (MNH) Assay
por: Zink, Annika, et al.
Publicado: (2020)