Genetic Inhibition of sFRP3 Prevents Glial Reactivity in a Mouse Model of Accelerated Aging

PURPOSE: Aging is the most significant risk factor for neurodegenerative disorders that are typified by cognitive deficits. Our recent work utilizing BubR1 hypomorphic (BubR1(H/H)) mice, an accelerated aging model, has revealed that genetic inhibition of the endogenous Wnt pathway inhibitor secreted...

Descripción completa

Detalles Bibliográficos
Autores principales: Corujo-Ramirez, Ana Mia, Dua, Malvika, Yoo, Ki Hyun, Oliveros, Alfredo, Jang, Mi-Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Continence Society 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731880/
https://www.ncbi.nlm.nih.gov/pubmed/33271003
http://dx.doi.org/10.5213/inj.2040436.218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731880/
https://www.ncbi.nlm.nih.gov/pubmed/33271003
http://dx.doi.org/10.5213/inj.2040436.218

Ejemplares similares