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Genetic Inhibition of sFRP3 Prevents Glial Reactivity in a Mouse Model of Accelerated Aging

PURPOSE: Aging is the most significant risk factor for neurodegenerative disorders that are typified by cognitive deficits. Our recent work utilizing BubR1 hypomorphic (BubR1(H/H)) mice, an accelerated aging model, has revealed that genetic inhibition of the endogenous Wnt pathway inhibitor secreted...

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Detalles Bibliográficos
Autores principales:	Corujo-Ramirez, Ana Mia, Dua, Malvika, Yoo, Ki Hyun, Oliveros, Alfredo, Jang, Mi-Hyeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Continence Society 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7731880/ https://www.ncbi.nlm.nih.gov/pubmed/33271003 http://dx.doi.org/10.5213/inj.2040436.218

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