Regulation of gene transcription by thyroid hormone receptor β agonists in clinical development for the treatment of non-alcoholic steatohepatitis (NASH)

Thyroid hormones are important modulators of metabolic activity in mammals and alter cholesterol and fatty acid levels through activation of the nuclear thyroid hormone receptor (THR). Currently, there are several THRβ agonists in clinical trials for the treatment of non-alcoholic steatohepatitis (N...

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Detalles Bibliográficos
Autores principales: Luong, Xuan G., Stevens, Sarah K., Jekle, Andreas, Lin, Tse-I, Gupta, Kusum, Misner, Dinah, Chanda, Sushmita, Mukherjee, Sucheta, Williams, Caroline, Stoycheva, Antitsa, Blatt, Lawrence M., Beigelman, Leonid N., Symons, Julian A., Raboisson, Pierre, McGowan, David, Vandyck, Koen, Deval, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732128/
https://www.ncbi.nlm.nih.gov/pubmed/33306682
http://dx.doi.org/10.1371/journal.pone.0240338

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732128/
https://www.ncbi.nlm.nih.gov/pubmed/33306682
http://dx.doi.org/10.1371/journal.pone.0240338

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