Xanthohumol Inhibits TGF-β1-Induced Cardiac Fibroblasts Activation via Mediating PTEN/Akt/mTOR Signaling Pathway

BACKGROUND: Xanthohumol (Xn) is the most abundant prenylated flavonoid in Hops (Humulus lupulus L.), and exhibits a range of pharmacological activities. This study aimed to investigate the effect of Xn on TGF-β1-induced cardiac fibroblasts activation and elucidate the underlying mechanism. MATERIALS...

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Detalles Bibliográficos
Autores principales: Jiang, Chuanhao, Xie, Ning, Sun, Taoli, Ma, Wanjun, Zhang, Bikui, Li, Wenqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732164/
https://www.ncbi.nlm.nih.gov/pubmed/33324040
http://dx.doi.org/10.2147/DDDT.S282206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732164/
https://www.ncbi.nlm.nih.gov/pubmed/33324040
http://dx.doi.org/10.2147/DDDT.S282206

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