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Piwi suppresses transcription of Brahma-dependent transposons via Maelstrom in ovarian somatic cells

Drosophila Piwi associates with PIWI-interacting RNAs (piRNAs) and represses transposons transcriptionally through heterochromatinization; however, this process is poorly understood. Here, we identify Brahma (Brm), the core adenosine triphosphatase of the SWI/SNF chromatin remodeling complex, as a n...

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Detalles Bibliográficos
Autores principales: Onishi, Ryo, Sato, Kaoru, Murano, Kensaku, Negishi, Lumi, Siomi, Haruhiko, Siomi, Mikiko C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732180/
https://www.ncbi.nlm.nih.gov/pubmed/33310860
http://dx.doi.org/10.1126/sciadv.aaz7420