A mathematical model of ctDNA shedding predicts tumor detection size

Early cancer detection aims to find tumors before they progress to an incurable stage. To determine the potential of circulating tumor DNA (ctDNA) for cancer detection, we developed a mathematical model of tumor evolution and ctDNA shedding to predict the size at which tumors become detectable. From...

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Detalles Bibliográficos
Autores principales: Avanzini, Stefano, Kurtz, David M., Chabon, Jacob J., Moding, Everett J., Hori, Sharon Seiko, Gambhir, Sanjiv Sam, Alizadeh, Ash A., Diehn, Maximilian, Reiter, Johannes G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732186/
https://www.ncbi.nlm.nih.gov/pubmed/33310847
http://dx.doi.org/10.1126/sciadv.abc4308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732186/
https://www.ncbi.nlm.nih.gov/pubmed/33310847
http://dx.doi.org/10.1126/sciadv.abc4308

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