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Rapid and ongoing evolution of repetitive sequence structures in human centromeres

Our understanding of centromere sequence variation across human populations is limited by its extremely long nested repeat structures called higher-order repeats that are challenging to sequence. Here, we analyzed chromosomes 11, 17, and X using long-read sequencing data for 36 individuals from dive...

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Detalles Bibliográficos
Autores principales: Suzuki, Yuta, Myers, Eugene W., Morishita, Shinichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732198/
https://www.ncbi.nlm.nih.gov/pubmed/33310858
http://dx.doi.org/10.1126/sciadv.abd9230