Elevated levels of extracellular vesicles in progranulin‐deficient mice and FTD‐GRN Patients

OBJECTIVE: The goal of this study was to investigate the effect of progranulin insufficiency on extracellular vesicles (EVs), a heterogeneous population of vesicles that may contribute to progression of neurodegenerative disease. Loss‐of‐function mutations in progranulin (GRN) are a major cause of f...

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Detalles Bibliográficos
Autores principales: Arrant, Andrew E., Davis, Skylar E., Vollmer, Rachael M., Murchison, Charles F., Mobley, James A., Nana, Alissa L., Spina, Salvatore, Grinberg, Lea T., Karydas, Anna M., Miller, Bruce L., Seeley, William W., Roberson, Erik D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732244/
https://www.ncbi.nlm.nih.gov/pubmed/33197149
http://dx.doi.org/10.1002/acn3.51242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732244/
https://www.ncbi.nlm.nih.gov/pubmed/33197149
http://dx.doi.org/10.1002/acn3.51242

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