Target RNA modification for epigenetic drug repositioning in neuroblastoma: computational omics proximity between repurposing drug and disease

RNA modifications modulate most steps of gene expression. However, little is known about its role in neuroblastoma (NBL) and the inhibitors targeting it. We analyzed the RNA-seq (n=122) and CNV data (n=78) from NBL patients in Therapeutically Applicable Research to Generate Effective Treatments (TAR...

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Detalles Bibliográficos
Autores principales: Ma, Pei, Yue, Lifeng, Zhang, Sen, Hao, Dacheng, Wu, Zhihong, Xu, Lijia, Du, Guanhua, Xiao, Peigen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732279/
https://www.ncbi.nlm.nih.gov/pubmed/33044945
http://dx.doi.org/10.18632/aging.103671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732279/
https://www.ncbi.nlm.nih.gov/pubmed/33044945
http://dx.doi.org/10.18632/aging.103671

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