Cargando…
Target RNA modification for epigenetic drug repositioning in neuroblastoma: computational omics proximity between repurposing drug and disease
RNA modifications modulate most steps of gene expression. However, little is known about its role in neuroblastoma (NBL) and the inhibitors targeting it. We analyzed the RNA-seq (n=122) and CNV data (n=78) from NBL patients in Therapeutically Applicable Research to Generate Effective Treatments (TAR...
Autores principales: | Ma, Pei, Yue, Lifeng, Zhang, Sen, Hao, Dacheng, Wu, Zhihong, Xu, Lijia, Du, Guanhua, Xiao, Peigen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732279/ https://www.ncbi.nlm.nih.gov/pubmed/33044945 http://dx.doi.org/10.18632/aging.103671 |
Ejemplares similares
-
Drug repositioning or target repositioning: A structural perspective of drug-target-indication relationship for available repurposed drugs
por: Parisi, Daniele, et al.
Publicado: (2020) -
Drug Repositioning for Diabetes Based on 'Omics' Data Mining
por: Zhang, Ming, et al.
Publicado: (2015) -
Unraveling Gene Fusions for Drug Repositioning in High-Risk Neuroblastoma
por: Liu, Zhichao, et al.
Publicado: (2021) -
Drug Repositioning for Alzheimer’s Disease Based on Systematic ‘omics’ Data Mining
por: Zhang, Ming, et al.
Publicado: (2016) -
Drug repositioning for dengue haemorrhagic fever by integrating multiple omics analyses
por: Amemiya, Takayuki, et al.
Publicado: (2019)