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Glypican-1-targeted and gemcitabine-loaded liposomes enhance tumor-suppressing effect on pancreatic cancer

Liposomes (LPs) as promising drug delivery systems are widely applied in cancer therapy. This study aimed to investigate the effect of glypican-1 (GPC1)-targeted and gemcitabine (GEM)-loaded LP [GPC1-LP (GEM)] on cell proliferation and apoptosis in PANC-1s, as well as on orthotopic pancreatic cancer...

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Detalles Bibliográficos
Autores principales: Mu, Yu, Wang, Dezhi, Bie, Liangyu, Luo, Suxia, Mu, Xiaoqian, Zhao, Yanqiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732280/
https://www.ncbi.nlm.nih.gov/pubmed/33035197
http://dx.doi.org/10.18632/aging.103918