S-allyl cysteine reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes and the destabilization of the medial meniscus model mice via the Nrf2 signaling pathway

In this study, we used murine chondrocytes as an in vitro model and mice exhibiting destabilization of the medial meniscus (DMM) as an in vivo model to investigate the mechanisms through which S-allyl cysteine (SAC) alleviates osteoarthritis (OA). SAC significantly reduced apoptosis and senescence a...

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Detalles Bibliográficos
Autores principales: Shao, Zhenxuan, Pan, Zongyou, Lin, Jialiang, Zhao, Qingqian, Wang, Yuqian, Ni, Libin, Feng, Shiyi, Tian, Naifeng, Wu, Yaosen, Sun, Liaojun, Gao, Weiyang, Zhou, Yifei, Zhang, Xiaolei, Wang, Xiangyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732291/
https://www.ncbi.nlm.nih.gov/pubmed/33027770
http://dx.doi.org/10.18632/aging.103757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732291/
https://www.ncbi.nlm.nih.gov/pubmed/33027770
http://dx.doi.org/10.18632/aging.103757

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