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S-allyl cysteine reduces osteoarthritis pathology in the tert-butyl hydroperoxide-treated chondrocytes and the destabilization of the medial meniscus model mice via the Nrf2 signaling pathway
In this study, we used murine chondrocytes as an in vitro model and mice exhibiting destabilization of the medial meniscus (DMM) as an in vivo model to investigate the mechanisms through which S-allyl cysteine (SAC) alleviates osteoarthritis (OA). SAC significantly reduced apoptosis and senescence a...
Autores principales: | Shao, Zhenxuan, Pan, Zongyou, Lin, Jialiang, Zhao, Qingqian, Wang, Yuqian, Ni, Libin, Feng, Shiyi, Tian, Naifeng, Wu, Yaosen, Sun, Liaojun, Gao, Weiyang, Zhou, Yifei, Zhang, Xiaolei, Wang, Xiangyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732291/ https://www.ncbi.nlm.nih.gov/pubmed/33027770 http://dx.doi.org/10.18632/aging.103757 |
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