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CircRNA CDR1as promotes hepatoblastoma proliferation and stemness by acting as a miR-7-5p sponge to upregulate KLF4 expression

Hepatoblastoma (HB) is a malignant embryonal tumor of the liver that consists of heterogenous populations of stem/progenitor cells. Although circular RNAs (circRNAs) play an essential role in tumor development, the effects of circRNA on the proliferation of HB cells, especially cancer stem cells (CS...

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Detalles Bibliográficos
Autores principales: Chen, Luping, Shi, Juanyi, Wu, Yaohao, Qiu, Ronglin, Zeng, Lexiang, Lou, Lei, Su, Jianhang, Liao, Minyi, Deng, Xiaogeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732296/
https://www.ncbi.nlm.nih.gov/pubmed/33052880
http://dx.doi.org/10.18632/aging.103748