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Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation

The contribution of dysregulated mitochondrial gene expression and consequent imbalance in biogenesis is not well understood in metabolic disorders such as insulin resistance and obesity. The ribosomal RNA maturation protein PTCD1 is essential for mitochondrial protein synthesis and its reduction ca...

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Detalles Bibliográficos
Autores principales: Perks, Kara L., Ferreira, Nicola, Ermer, Judith A., Rudler, Danielle L., Richman, Tara R., Rossetti, Giulia, Matthews, Vance B., Ward, Natalie C., Rackham, Oliver, Filipovska, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732297/
https://www.ncbi.nlm.nih.gov/pubmed/33024056
http://dx.doi.org/10.18632/aging.104010