Cargando…
Reduced mitochondrial translation prevents diet-induced metabolic dysfunction but not inflammation
The contribution of dysregulated mitochondrial gene expression and consequent imbalance in biogenesis is not well understood in metabolic disorders such as insulin resistance and obesity. The ribosomal RNA maturation protein PTCD1 is essential for mitochondrial protein synthesis and its reduction ca...
Autores principales: | Perks, Kara L., Ferreira, Nicola, Ermer, Judith A., Rudler, Danielle L., Richman, Tara R., Rossetti, Giulia, Matthews, Vance B., Ward, Natalie C., Rackham, Oliver, Filipovska, Aleksandra |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732297/ https://www.ncbi.nlm.nih.gov/pubmed/33024056 http://dx.doi.org/10.18632/aging.104010 |
Ejemplares similares
-
Fidelity of translation initiation is required for coordinated respiratory complex assembly
por: Rudler, Danielle L., et al.
Publicado: (2019) -
Murine cytomegalovirus infection exacerbates complex IV deficiency in a model of mitochondrial disease
por: Ferreira, Nicola, et al.
Publicado: (2020) -
Mutation in MRPS34 Compromises Protein Synthesis and Causes Mitochondrial Dysfunction
por: Richman, Tara R., et al.
Publicado: (2015) -
Multi‐omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer
por: Stentenbach, Maike, et al.
Publicado: (2023) -
Adult-onset obesity is triggered by impaired mitochondrial gene expression
por: Perks, Kara L., et al.
Publicado: (2017)