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Knockdown of NHP2 inhibits hepatitis B virus X protein-induced hepatocarcinogenesis via repressing TERT expression and disrupting the stability of telomerase complex

Hepatitis B virus X protein (HBx) is highly expressed in HBV-infected hepatocellular carcinoma (HCC) and upregulates transcriptional activation of telomerase reverse transcriptase (TERT). NHP2 is a component of the telomerase complex and also increased in HCC. However, whether NHP2 could accelerate...

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Detalles Bibliográficos
Autores principales:	Tang, Shuming, Wu, Weigang, Wan, Haoqiang, Wu, Xuecheng, Chen, Haixia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732313/ https://www.ncbi.nlm.nih.gov/pubmed/33044946 http://dx.doi.org/10.18632/aging.103810

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