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Mapping the Multi-Organ miRNA-mRNA Regulatory Network in LPS-Mediated Endotoxemic Mice: Exploring the Shared Underlying Key Genes and Mechanisms

BACKGROUND: To this day, the molecular mechanism of endotoxin-induced multi-organ failure has not been completely clarified. This study aimed to construct an miRNA-mRNA regulatory network and identify main pathways and key genes in multi-organ of LPS-mediated endotoxemic mice. METHODS: Public datase...

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Detalles Bibliográficos
Autores principales: Zhang, Cong, Liao, Ying, Liu, Zhihao, Zeng, Lijin, Peng, Zhihua, Liao, Jinli, Yang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732439/
https://www.ncbi.nlm.nih.gov/pubmed/33330617
http://dx.doi.org/10.3389/fmolb.2020.573327