Cellular and Mathematical Analyses of LUBAC Involvement in T Cell Receptor-Mediated NF-κB Activation Pathway

The LUBAC ubiquitin ligase complex, composed of the HOIP, HOIL-1L, and SHARPIN subunits, stimulates the canonical nuclear factor-κB (NF-κB) activation pathways through its Met1-linked linear ubiquitination activity. Here we performed cellular and mathematical modeling analyses of the LUBAC involveme...

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Detalles Bibliográficos
Autores principales: Oikawa, Daisuke, Hatanaka, Naoya, Suzuki, Takashi, Tokunaga, Fuminori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732508/
https://www.ncbi.nlm.nih.gov/pubmed/33329596
http://dx.doi.org/10.3389/fimmu.2020.601926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732508/
https://www.ncbi.nlm.nih.gov/pubmed/33329596
http://dx.doi.org/10.3389/fimmu.2020.601926

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