Cargando…

Backstepping Mechanism of Kinesin-1

Kinesin-1 is an ATP-driven molecular motor that transports cellular cargo along microtubules. At low loads, kinesin-1 almost always steps forward, toward microtubule plus ends, but at higher loads, it can also step backward. Backsteps are usually 8 nm but can be larger. These larger backward events...

Descripción completa

Detalles Bibliográficos
Autores principales: Toleikis, Algirdas, Carter, Nicholas J., Cross, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732724/
https://www.ncbi.nlm.nih.gov/pubmed/33091340
http://dx.doi.org/10.1016/j.bpj.2020.09.034