Comparative proteomic analysis highlights metabolic dysfunction in α-synucleinopathy

The synaptic protein α-synuclein is linked through genetics and neuropathology to the pathogenesis of Parkinson’s disease and related disorders. However, the mechanisms by which α-synuclein influences disease onset and progression are incompletely understood. To identify pathogenic pathways and ther...

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Detalles Bibliográficos
Autores principales: Sarkar, Souvarish, Murphy, Michael A., Dammer, Eric B., Olsen, Abby L., Rangaraju, Srikant, Fraenkel, Ernest, Feany, Mel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732845/
https://www.ncbi.nlm.nih.gov/pubmed/33311497
http://dx.doi.org/10.1038/s41531-020-00143-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732845/
https://www.ncbi.nlm.nih.gov/pubmed/33311497
http://dx.doi.org/10.1038/s41531-020-00143-w

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