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RNA-binding protein SORBS2 suppresses clear cell renal cell carcinoma metastasis by enhancing MTUS1 mRNA stability

RNA-binding proteins (RBPs) predominantly contribute to abnormal posttranscriptional gene modulation and disease progression in cancer. Sorbin and SH3 domain-containing 2 (SORBS2), an RBP, has been reported to be a potent tumor suppressor in several cancer types. Through integrative analysis of clin...

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Detalles Bibliográficos
Autores principales: Lv, Qi, Dong, Fan, Zhou, Yong, Cai, Zhiping, Wang, Gangmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732854/
https://www.ncbi.nlm.nih.gov/pubmed/33311452
http://dx.doi.org/10.1038/s41419-020-03268-1