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Receptor-targeted engineered probiotics mitigate lethal Listeria infection

Probiotic bacteria reduce the intestinal colonization of pathogens. Yet, their use in preventing fatal infection caused by foodborne Listeria monocytogenes (Lm), is inconsistent. Here, we bioengineered Lactobacillus probiotics (BLP) to express the Listeria adhesion protein (LAP) from a non-pathogeni...

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Detalles Bibliográficos
Autores principales: Drolia, Rishi, Amalaradjou, Mary Anne Roshni, Ryan, Valerie, Tenguria, Shivendra, Liu, Dongqi, Bai, Xingjian, Xu, Luping, Singh, Atul K., Cox, Abigail D., Bernal-Crespo, Victor, Schaber, James A., Applegate, Bruce M., Vemulapalli, Ramesh, Bhunia, Arun K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732855/
https://www.ncbi.nlm.nih.gov/pubmed/33311493
http://dx.doi.org/10.1038/s41467-020-20200-5