Cargando…

Sirt6-Mediated Endothelial-to-Mesenchymal Transition Contributes Toward Diabetic Cardiomyopathy via the Notch1 Signaling Pathway

BACKGROUND: Endothelial-to-mesenchymal transition (EndMT) is an important source of myofibroblasts that directly affects cardiac function in diabetic cardiomyopathy (DCM) via an unknown underlying mechanism. Sirt6 is a member of the Sirtuin family of NAD(+)-dependent enzymes that plays an important...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yan, Dong, Yuan, Xiong, Zhenyu, Zhu, Zhengru, Gao, Fanya, Wang, Tingting, Man, Wanrong, Sun, Dong, Lin, Jie, Li, Tongbin, Li, Congye, Zhao, Zhijing, Shen, Min, Sun, Dongdong, Fan, Yanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732976/
https://www.ncbi.nlm.nih.gov/pubmed/33324079
http://dx.doi.org/10.2147/DMSO.S287287