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Sirt6-Mediated Endothelial-to-Mesenchymal Transition Contributes Toward Diabetic Cardiomyopathy via the Notch1 Signaling Pathway

BACKGROUND: Endothelial-to-mesenchymal transition (EndMT) is an important source of myofibroblasts that directly affects cardiac function in diabetic cardiomyopathy (DCM) via an unknown underlying mechanism. Sirt6 is a member of the Sirtuin family of NAD(+)-dependent enzymes that plays an important...

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Detalles Bibliográficos
Autores principales:	Zhang, Yan, Dong, Yuan, Xiong, Zhenyu, Zhu, Zhengru, Gao, Fanya, Wang, Tingting, Man, Wanrong, Sun, Dong, Lin, Jie, Li, Tongbin, Li, Congye, Zhao, Zhijing, Shen, Min, Sun, Dongdong, Fan, Yanhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732976/ https://www.ncbi.nlm.nih.gov/pubmed/33324079 http://dx.doi.org/10.2147/DMSO.S287287

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