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Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system

Depression is the leading cause of disability worldwide. Recent observations have revealed an association between mood disorders and alterations of the intestinal microbiota. Here, using unpredictable chronic mild stress (UCMS) as a mouse model of depression, we show that UCMS mice display phenotypi...

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Detalles Bibliográficos
Autores principales: Chevalier, Grégoire, Siopi, Eleni, Guenin-Macé, Laure, Pascal, Maud, Laval, Thomas, Rifflet, Aline, Boneca, Ivo Gomperts, Demangel, Caroline, Colsch, Benoit, Pruvost, Alain, Chu-Van, Emeline, Messager, Aurélie, Leulier, François, Lepousez, Gabriel, Eberl, Gérard, Lledo, Pierre-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7732982/
https://www.ncbi.nlm.nih.gov/pubmed/33311466
http://dx.doi.org/10.1038/s41467-020-19931-2