A P2rx7 Passenger Mutation Affects the Vitality and Function of T cells in Congenic Mice

Among laboratory mouse strains many genes are differentially expressed in the same cell population. As consequence, gene targeting in 129-derived embryonic stem cells (ESCs) and backcrossing the modified mice onto the C57BL/6 background can introduce passenger mutations in the close proximity of the...

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Detalles Bibliográficos
Autores principales: Er-Lukowiak, Marco, Duan, Yinghui, Rassendren, Francois, Ulmann, Lauriane, Nicke, Annette, Ufer, Friederike, Friese, Manuel A., Koch-Nolte, Friedrich, Magnus, Tim, Rissiek, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733020/
https://www.ncbi.nlm.nih.gov/pubmed/33336163
http://dx.doi.org/10.1016/j.isci.2020.101870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733020/
https://www.ncbi.nlm.nih.gov/pubmed/33336163
http://dx.doi.org/10.1016/j.isci.2020.101870

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