Insulin-regulated aminopeptidase deficiency impairs cardiovascular adaptations and placental development during pregnancy

Insulin-regulated aminopeptidase (IRAP), an enzyme that cleaves vasoactive peptides including oxytocin and vasopressin, is suggested to play a role in pregnancy and the onset of preeclampsia. Our aim was to examine the contribution of IRAP to arterial pressure regulation and placental development du...

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Detalles Bibliográficos
Autores principales: Walton, Sarah L., Mirabito Colafella, Katrina M., Ansari, Aneesa, Chai, Siew Yeen, Denton, Kate M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Cardiovascular System & Vascular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733041/
https://www.ncbi.nlm.nih.gov/pubmed/33252660
http://dx.doi.org/10.1042/CS20201233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733041/
https://www.ncbi.nlm.nih.gov/pubmed/33252660
http://dx.doi.org/10.1042/CS20201233

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