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Insulin-regulated aminopeptidase deficiency impairs cardiovascular adaptations and placental development during pregnancy
Insulin-regulated aminopeptidase (IRAP), an enzyme that cleaves vasoactive peptides including oxytocin and vasopressin, is suggested to play a role in pregnancy and the onset of preeclampsia. Our aim was to examine the contribution of IRAP to arterial pressure regulation and placental development du...
Autores principales: | Walton, Sarah L., Mirabito Colafella, Katrina M., Ansari, Aneesa, Chai, Siew Yeen, Denton, Kate M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733041/ https://www.ncbi.nlm.nih.gov/pubmed/33252660 http://dx.doi.org/10.1042/CS20201233 |
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