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EPHA mutation as a predictor of immunotherapeutic efficacy in lung adenocarcinoma

BACKGROUND: Ephrin type-A receptors (EPHA) are members of family of receptor tyrosine kinases and are related to tumor immunogenicity and immune microenvironment, however, the association between EPHA mutation (EPHA(mut)) and efficacy of immune checkpoint inhibitors (ICIs) has not been investigated...

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Detalles Bibliográficos
Autores principales: Bai, Hua, Duan, Jianchun, Li, Chengcheng, Xie, Wenzhuan, Fang, Wenfeng, Xu, Yu, Wang, Guoqiang, Wan, Rui, Sun, Jing, Xu, Jiachen, Wang, Xin, Fei, Kailun, Zhao, Zhengyi, Cai, Shangli, Zhang, Li, Wang, Jie, Wang, Zhijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733211/
https://www.ncbi.nlm.nih.gov/pubmed/33303576
http://dx.doi.org/10.1136/jitc-2020-001315