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Circ_0003998 enhances doxorubicin resistance in hepatocellular carcinoma by regulating miR-218-5p/EIF5A2 pathway

BACKGROUND: The involvement of circular RNAs (circRNAs) in chemoresistance of tumors has been identified. Herein, this study aims to investigate the role and the underlying mechanism of circ_0003998 in doxorubicin (DOX) resistance in hepatocellular carcinoma (HCC). METHODS: The expression of circ_00...

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Detalles Bibliográficos
Autores principales: Li, Xiaomin, He, Jiefeng, Ren, Xiaojing, Zhao, Haichao, Zhao, Haoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733254/
https://www.ncbi.nlm.nih.gov/pubmed/33308276
http://dx.doi.org/10.1186/s13000-020-01056-1