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Label-free vibrational imaging of different Aβ plaque types in Alzheimer’s disease reveals sequential events in plaque development

The neuropathology of Alzheimer’s disease (AD) is characterized by hyperphosphorylated tau neurofibrillary tangles (NFTs) and amyloid-beta (Aβ) plaques. Aβ plaques are hypothesized to follow a development sequence starting with diffuse plaques, which evolve into more compact plaques and finally matu...

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Detalles Bibliográficos
Autores principales: Röhr, Dominik, Boon, Baayla D. C., Schuler, Martin, Kremer, Kristin, Hoozemans, Jeroen J. M., Bouwman, Femke H., El-Mashtoly, Samir F., Nabers, Andreas, Großerueschkamp, Frederik, Rozemuller, Annemieke J. M., Gerwert, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733282/
https://www.ncbi.nlm.nih.gov/pubmed/33308303
http://dx.doi.org/10.1186/s40478-020-01091-5