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Structure-based dynamic analysis of the glycine cleavage system suggests key residues for control of a key reaction step

Molecular shuttles play decisive roles in many multi-enzyme systems such as the glycine cleavage system (GCS) for one-carbon (C1) metabolism. In GCS, a lipoate swinging arm containing an aminomethyl moiety is attached to protein H and serves as a molecular shuttle among different proteins. Protectio...

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Detalles Bibliográficos
Autores principales: Zhang, Han, Li, Yuchen, Nie, Jinglei, Ren, Jie, Zeng, An-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733448/
https://www.ncbi.nlm.nih.gov/pubmed/33311647
http://dx.doi.org/10.1038/s42003-020-01401-6