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Structure-based dynamic analysis of the glycine cleavage system suggests key residues for control of a key reaction step
Molecular shuttles play decisive roles in many multi-enzyme systems such as the glycine cleavage system (GCS) for one-carbon (C1) metabolism. In GCS, a lipoate swinging arm containing an aminomethyl moiety is attached to protein H and serves as a molecular shuttle among different proteins. Protectio...
Autores principales: | Zhang, Han, Li, Yuchen, Nie, Jinglei, Ren, Jie, Zeng, An-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733448/ https://www.ncbi.nlm.nih.gov/pubmed/33311647 http://dx.doi.org/10.1038/s42003-020-01401-6 |
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