Cargando…
Hdac3 deletion in myeloid progenitor cells enhances bone healing in females and limits osteoclast fusion via Pmepa1
Previous studies examining the role of the histone deacetylase Hdac3 within myeloid cells demonstrated that Hdac3 promotes M2 activation and tissue healing in inflammatory conditions. Since myeloid lineage cells are required for proper bone formation and regeneration, in this study we examined the f...
Autores principales: | Molstad, David H. H., Zars, Elizabeth, Norton, Andrew, Mansky, Kim C., Westendorf, Jennifer J., Bradley, Elizabeth W. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7733476/ https://www.ncbi.nlm.nih.gov/pubmed/33311522 http://dx.doi.org/10.1038/s41598-020-78364-5 |
Ejemplares similares
-
Phlpp1 is induced by estrogen in osteoclasts and its loss in Ctsk-expressing cells does not protect against ovariectomy-induced bone loss
por: Hanson, Marcelline K., et al.
Publicado: (2021) -
Myeloid Lineage Ablation of Phlpp1 Regulates M-CSF Signaling and Tempers Bone Resorption in Female Mice
por: Karkache, Ismael Y., et al.
Publicado: (2021) -
Conditional Loss of MEF2C Expression in Osteoclasts Leads to a Sex-Specific Osteopenic Phenotype
por: Maisuria, Ravi, et al.
Publicado: (2023) -
Class II and IV HDACs function as inhibitors of osteoclast differentiation
por: Blixt, Nicholas C., et al.
Publicado: (2017) -
Epigenetic Regulators Involved in Osteoclast Differentiation
por: Astleford, Kristina, et al.
Publicado: (2020)